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Areas of specialization
Exercise science; exercise physiology
Academic degrees
- Doctor of medicine, University of Wisconsin
(Madison), 1957.
- Master of science (Biochemistry), University of
Wisconsin (Madison), 1954.
- Bachelor of science (Chemistry), Summa Cum Laude,
University of Florida (Gainesville) 1952.
Postdoctoral training
- Rotating internship, Henry Ford Hospital, Detroit, MI
1957-58.
- Internal Medicine, The Lahey Clinic, Boston, MA,
1958-60.
- Cardiology, University of Miami School of Medicine and
Jackson Memorial Hospital, Miami, Fl, 1960-61.
- Research fellow in Cardiovascular Physiology , Walter
Reed Army Institute of Research (WRAIR), Washington, DC,
1964-67.
Professional experience
- Medical officer, US Army Reserve 1957-1991; Highest Rank
Attained, Colonel, MC (Retired).
- Active duty, US Medical Corps as Cardiology Consultant
for US Armed Forces in France and Chief of Medicine,
Outpatient Services and Internship Training at 34th General
Hospital, Orleans, France, 1961-64, as Research Fellow WRAIR
1964-67 (see above), and as cardiologist, Fizsimmons US Army
Medical Center, Denver CO, during 1990-91 (Desert
Shield/Storm).
- Instructor to associate professor, New Jersey College of
Medicine (Newark) and Director of Clinical Research Center,
Newark Beth Israel Medical Center, 1967-73.
Publications
Author of about 200 articles in refereed professional
journals, about 50 book chapters, 126 published abstracts,
and primary co-author or editor on 2 books.
Selected publications
Leon AS: Benefits of exercise training for
patients following a myocardial infarction. J. Sports Med.
1999 (In Press).
Leon AS, Rice T, Mandel, S et al: Blood
lipid response to 20 weeks of supervised exercise in a large
biracial population: The HERITAGE Family Study. Metabolism
1999 (In press).
Leon, AS (Associate Scientific Editor and
Contributor). The Surgeon General's Report. Physical Activity
and Health.
US Government Printing Office, 1996.
Leon, AS, Richardson, M.: Exercise, Health,
and Disease. In Clinical Exercise Testing and Prescription,
Theory and Application. S.O. Roberts, R.A. Robergs, P.
Hanson (eds), CRC Press, Boca Raton, FL 1997, pp. 281- 302.
Leon, AS, Myers, MJ, Connett, J.:
Leisure-time physical activity and the 16-year risks of
mortality from CHD and all causes in the MRFIT. Intern J.
Sports Med. 18 (Supple 3): S139-S254, 1997.
Leon, AS (Ed): Proceedings of the NIH
Consensus Development Conference on Physical Activity and
Cardiovascular Health and author of paper, "Contribution of
moderate intensity PA to reduced risk of CHD". Champaign, IL,
Human Kinetics, February 1997.
Leon, AS, Casal, D., Jacobs, D.R. Jr.:
Effects of 2000 kilocalories per week of walking and stair
climbing on physical fitness and risk factors for coronary heart
disease. J. Cardiopulmonary Rehab. 16:183-192, 1996.
Santiago, M.C., Leon, A.S., Serfass, R.C.:
Failure of 40 weeks of brisk walking to alter blood lipids in
nomoipidemic women. Canadian J. Appl. Res. 20: 417-428,
1995.
Design, and Measurement Protocol. Med. Sci
Sports 27: 721-729, 1995.
Richardson MT, Leon AS, Jacobs DR Jr,
Ainsworth BE, Serfass RC: Comprehensive evaluation of Minnesota
Leisure Time Physical Activity Questionnaire. J Clin
Epidemiol 47: 271-281, 1994.
Ainsworth BE, Leon AS, Richardson MT, Jacobs
Jr DR, Paffenbarger Jr RS: Accuracy of the College Alumnus
Physical Activity Questionnaire. Internl. J. Clin. Epidemiol.
46: 1403-1411, 1993.
Jacobs DR Jr, Ainsworth BE, Hartman TJ, Leon
AS: A simultaneous evaluation of 10 commonly used physical
activity questionnaires. Med.Sci.Sports Exer. 25: 92-98,
1993.
Leon AS: Diabetes. In: Exercise Testing
and Exercise Prescription for Special Cases. 2nd Edition. JS
Skinner (Ed), Lea & Febiger, Philadelphia, 1993.
Leon AS & Hamm L: Exercise Prescription. In:
Rehabilitation of the Coronary Patient. Third Edition. H
Hellerstein & NK Wenger (Eds), Churchill Livingstone, NY, 1992.
Leon, AS: Recent advances in the management
of hypertension. J Cardiopulm. Rehab. 11: 182-191, 1991.
14.
Smith TW & Leon AS: Coronary Heart
Disease. A Behavioral Perspective. Res. Press, Champaign,
Il, 1992.
Leon AS & Connett J: Physical activity
status and 10.5 year mortality rate in the MRFIT. Internat J
Epidemol
20: 690-697, 1991.
Leon AS: Role of physical activity in
prevention and management of obesity. In: Sports Medicine,
2nd Edition, A J Ryan & L Allman (Eds), Academic Press,
Orlando, 1989, pp. 593-617.
Leon AS, Connett J, Jacobs DR Jr & Rauramaa
R: Leisure-time physical activity levels and risk of coronary
heart disease and death in the multiple risk factor intervention
trial.
JAMA 258: 2388-2395, 1987.
Santiago MC, Alexander JF, Stull GA, Serfass
RC, Hayday Am & Leon AS: Physiological response of sedentary
women to a 20-week conditioning program of walking or jogging.
Scand J Sports Med 9: 33-39, 1987.
Leon AS, McNally C, Casal DC, Grimm R, Crow
R, Bell C & Hunninghake DB: Enalapril alone and combined with
hydrochlorothiazide in the treatment of hypertension: Effect on
treadmill exercise performance. J Cardiac Rehab 6:
251-256, 1986.
Sopko G, Leon AS, Jacobs DR Jr, Foster N,
Moy J, Kuba K, Anderson JT, Casal DC, McNally C & Frantz I:
Effects of exercise and weight loss on plasma lipids in young
obese men.
Metabolism 34: 227-236, 1985.
Leon AS, Conrad J, Casal DC, Serfass, RC,
Bonnard RA, Goetz FC & Blackburn H: Exercise for diabetics:
Effects of conditioning at constant body weight. J Cardiac
Rehab 4: 278-286, 1984.
Leon AS & Blackburn H: Physical activity and
hypertension. In: Preventive Cardiology, NH Kaplan & J
Stamler (Eds), W B Saunders Co, Philadelphia, 1983, p. 86-97.
Leon AS, DeBacker G & Taylor HL:
Relationship of physical characteristics and life habits to
treadmill exercise capacity. Am J Epidemiol 113: 536-660,
1981.
Leon AS, Conrad J, Serfass R & Hunninghake
DB: Effects of vigorous walking program on body composition and
carbohydrate and lipid metabolism of obese young men. Am J
Clin Nutr 32:
1776- 1787, 1979.
Leon AS & Bloor CM: Effects of daily and
intermittent exercise and its cessation of heart and
vasculature. J Appl Physiol 24: 485-490, 1968.
Leon AS & Bloor CM: Quantitative analysis of
coronary artery inheritance. J Heredity 59: 48-52, 1965.
Research
- Principal Investigator (PI) on five major, multi-year
National Institutes of Health and two major American Heart
Association (AHA) national grants, and 6 internal.
- University of Minnesota Biological Research Grants while
at the University of Minnesota, 1973 to present, involving
assessment of physical activity and the effects of exercise
training on risk factors for coronary heart disease and
diabetes mellitus.
- Co-investigator on many other major NIH funded studies
on primary and secondary heart attack prevention, including
MRFIT and LRC Coronary Primary Prevention Trial, and the
Program on Surgical Control of Hyperlipidemia (POSCH).
- Currently PI on the NIH-funded Genetics, Risk Factors
and Exercise. The
- HERITAGE Family Study, 1991-2000, (2.5 million dollars)
and AHA-funded Physicianís Exercise Promotion Study (PEPS)
in collaboration with Park-Nicollet Clinics (Health
Partners) 1999-2002 ($450,000). PI, Co-PI or Investigator on
dozens of additional grants from the pharmaceutical industry
primarily involving hypertension and blood lipid management
to reduce risk of heart disease.
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